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KMID : 0356920220750010086
Korean Journal of Anesthesiology
2022 Volume.75 No. 1 p.86 ~ p.96
Heart rate variability follow-up during COVID-19 -a case report-
Gutierrez Alejandro Figar

Bonofiglio Francisco C.
Karippacheril John George
Redelico Francisco O.
de Los Angeles Iturralde Maria
Abstract
Background: To detect an early increase in the inflammatory response might prove to be vital for mitigating the deleterious effects of the disease over time.

Case: A 52-year-old obese man with moderate asthma and hypertension, who developed COVID-19 and had moderate symptoms, used a wearable device to record heart rate variability (HRV) during his illness. He had low parasympathetic tone, which decreased daily until it reached almost 2 standard deviations (SD) below normal values at the end of the second week. His sympathetic tone increased from > 3 SD to > 5 SD.

Conclusions: These findings suggest an altered modulation of the sympathetic and parasympathetic nervous systems in COVID-19, such that the sympathetic tone is augmented and the parasympathetic tone is reduced. Population norms of COVID-19 infections should be further studied over the short-term and using 24 h HRV measurements.
KEYWORD
Ambulatory monitoring, Autonomic nervous system, Computer-assisted signal processing, COVID-19, Heart rate, Wearable electronic devices
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